Subcostal view with a tilt can image the inferior vena cava (IVC) draining into the right atrium (RA). Here the IVC is grossly dilated, with a diameter of 40 mm, indicating severe right heart failure. When IVC is dilated very much it is customary to add 20 mm Hg to the observed tricuspid regurgitation gradient while estimating the right ventricular systolic pressure. Dilated IVC without an inspiratory collapse is known as IVC plethora. IVC can be dilated in constricted pericarditis, without associated enlargement of right heart chambers. Zig-zag movement of sonodense particles in a dilated IVC in constrictive pericarditis has been called the traffic jam sign.
IVC measurement is often used to guide fluid resuscitation in the acute care setting instead of the conventional measurement of central venous pressure by a catheter. This is convenient being non-invasive and easily available in modern day emergency care units equipped with a point of care ultrasound machine. In a person presenting with hypotension, if IVC is collapsed, a fluid bolus can be given fast, often with rapid recovery.